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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLD1
All Species:
21.82
Human Site:
Y966
Identified Species:
32
UniProt:
Q13393
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13393
NP_001123553.1
1074
124184
Y966
C
F
R
V
V
L
G
Y
L
D
D
P
S
E
D
Chimpanzee
Pan troglodytes
XP_526380
1125
128795
Y1017
C
F
R
V
V
L
G
Y
L
D
D
P
S
E
D
Rhesus Macaque
Macaca mulatta
XP_001085464
1074
124020
Y966
C
F
R
V
V
L
G
Y
L
D
D
P
S
E
D
Dog
Lupus familis
XP_545291
1075
123911
Y967
C
F
R
V
V
L
G
Y
L
S
D
P
S
E
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z280
1074
123950
Y966
C
F
R
L
V
L
G
Y
L
S
D
P
S
E
D
Rat
Rattus norvegicus
P70496
1074
123795
Y966
C
F
R
L
V
L
G
Y
L
S
D
P
S
E
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513744
295
33781
G225
R
S
L
Q
T
G
V
G
E
L
H
G
E
T
R
Chicken
Gallus gallus
XP_422793
1072
123414
G964
R
C
F
R
V
V
L
G
G
S
D
L
N
P
D
Frog
Xenopus laevis
NP_001129642
1039
119219
C931
C
F
R
L
I
L
G
C
L
N
D
P
S
A
N
Zebra Danio
Brachydanio rerio
NP_001153567
1022
117847
A914
C
F
K
T
I
L
G
A
F
T
D
P
S
I
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001137610
1364
155352
G1256
L
G
L
L
E
S
E
G
S
S
R
S
D
L
D
Honey Bee
Apis mellifera
XP_001121004
1135
129725
F1027
F
S
E
H
L
G
L
F
K
T
N
E
D
I
D
Nematode Worm
Caenorhab. elegans
NP_494939
1427
163517
A1319
L
P
D
S
R
R
K
A
K
F
P
Y
A
V
S
Sea Urchin
Strong. purpuratus
XP_784455
790
90080
C720
I
Y
D
E
V
F
K
C
I
P
T
D
R
A
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M9W8
1046
118792
L922
L
W
S
E
H
L
G
L
H
A
G
E
I
Q
K
Baker's Yeast
Sacchar. cerevisiae
P36126
1683
195185
E1460
N
E
K
S
N
E
G
E
S
T
N
V
D
Q
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.7
97.8
91
N.A.
91
90.6
N.A.
22
79.4
75.6
66.6
N.A.
34.8
40.3
35.9
35.1
Protein Similarity:
100
92
99
95.1
N.A.
95.6
95.6
N.A.
24.8
88.8
86.3
78.3
N.A.
50.9
57.7
51
49.5
P-Site Identity:
100
100
100
86.6
N.A.
86.6
86.6
N.A.
0
20
60
53.3
N.A.
6.6
6.6
0
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
0
33.3
86.6
66.6
N.A.
13.3
26.6
6.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.6
21
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50.6
35.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
13
0
7
0
0
7
13
0
% A
% Cys:
50
7
0
0
0
0
0
13
0
0
0
0
0
0
0
% C
% Asp:
0
0
13
0
0
0
0
0
0
19
57
7
19
0
63
% D
% Glu:
0
7
7
13
7
7
7
7
7
0
0
13
7
38
0
% E
% Phe:
7
50
7
0
0
7
0
7
7
7
0
0
0
0
0
% F
% Gly:
0
7
0
0
0
13
63
19
7
0
7
7
0
0
0
% G
% His:
0
0
0
7
7
0
0
0
7
0
7
0
0
0
0
% H
% Ile:
7
0
0
0
13
0
0
0
7
0
0
0
7
13
0
% I
% Lys:
0
0
13
0
0
0
13
0
13
0
0
0
0
0
7
% K
% Leu:
19
0
13
25
7
57
13
7
44
7
0
7
0
7
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
0
0
0
7
0
0
0
0
7
13
0
7
0
13
% N
% Pro:
0
7
0
0
0
0
0
0
0
7
7
50
0
7
0
% P
% Gln:
0
0
0
7
0
0
0
0
0
0
0
0
0
13
0
% Q
% Arg:
13
0
44
7
7
7
0
0
0
0
7
0
7
0
7
% R
% Ser:
0
13
7
13
0
7
0
0
13
32
0
7
50
0
7
% S
% Thr:
0
0
0
7
7
0
0
0
0
19
7
0
0
7
7
% T
% Val:
0
0
0
25
50
7
7
0
0
0
0
7
0
7
0
% V
% Trp:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
0
0
0
0
0
38
0
0
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _